Friday, April 2, 2010

The difference between allergy and intolerance


A few months ago we wrote on ALCAT.com about the difference between food intolerance and food allergy.  We wanted to re-post that information here because it's important to distinguish between the two.  So, here you go...

What is food sensitivity?

The inability to tolerate foods and environmental factors, also known as sensitivity or intolerance, induces chronic activation of the innate immune system and gives rise to inflammatory processes, which includes excess production of reactive oxygen species and the release of preformed and newly synthesized mediators of inflammation.


This inflammation has been linked to countless chronic conditions, including:  digestive disorders, migraines, obesity, chronic fatigue, ADD, aching joints, skin disorders, arthritis and many more.


How does food sensitivity differ from classic food allergies?  


True food allergies refer to foods that trigger the immune system to acutely produce massive amounts of the chemical histamine that leads to anaphylaxis.  This potentially fatal condition causes the throat and esophagus to swell, cutting off air from the lungs, or may simply cause hives, skin rashes, and other non-life-threatening reactions.


This type of reaction is called a type I hypersensitivity reaction, caused by the degranulation of mast cells or basophils that is mediated by Immunoglobulin E (IgE).